We haven't listed all the side effects here. They also depend on what other treatment you are having.Ĭontact your healthcare team immediately if you have signs of infection, including a temperature above 37.5C or below 36C. How often and how severe the side effects are can vary from person to person. You usually have one of these before starting treatment and every 3 months during treatment. You usually have heart tests such as an echocardiogram (ECHO) or a multigated acquisition (MUGA) scan to build up a picture of how well your heart if working. They also check how well your liver and kidneys are working. They check your levels of blood cells and other substances in the blood. You have blood tests before and during your treatment. Your healthcare team will go through this with you. If you're having radiotherapy as well as trastuzumab emtansine your treatment is usually spaced to reduce the risk of having radiation related side effects. If you're having trastuzumab emtansine after surgery for early breast cancer you might have up to 14 cycles.įor breast cancer that has come back or spread around the body, you continue to have treatment for as long as it helps and the side effects aren't too bad. If the first one went well you might have the next treatments over 30 minutes. You usually have your first treatment as an inpatient to monitor you for any reactions to the drug. You have the first treatment over 90 minutes. You have trastuzumab emtansine once every 3 weeks, this is one cycle of treatment. The tube stays in place throughout the course of treatment. Or you might have treatment through a long line: a central line, a PICC line or a portacath. These are long plastic tubes that give the drug into a large vein in your chest. You have treatment through a thin short tube (a cannula) that goes into a vein in your arm each time you have treatment. You have trastuzumab emtansine as a drip into your bloodstream (intravenously). Inside the cell emtansine becomes active and kills the cancer cell. When this happens it allows the emtansine to go into the cancer cell. Trastuzumab attaches to the HER2 receptor. Some breast cancers have too much of a protein called human epidermal growth factor receptor 2 (HER2) on the surface of their cells. Emtansine is a cancer drug that becomes active once it enters the cancer cell. Trastuzumab is a type of targeted cancer drug (biological therapy) called monoclonal antibody. Find out more about trastuzumab (Herceptin, Herzuma, Ontruzant).
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